{"id":190,"date":"2019-05-21T06:12:58","date_gmt":"2019-05-21T06:12:58","guid":{"rendered":"http:\/\/www.ionfarms.com\/?page_id=190"},"modified":"2023-12-27T14:30:28","modified_gmt":"2023-12-27T05:30:28","slug":"studies","status":"publish","type":"page","link":"https:\/\/ionfarms.com\/studies\/","title":{"rendered":"studies"},"content":{"rendered":"\t\t
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Studies<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Alkaline Water<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Hamasaki, Takeki, et al. \u201cElectrochemically Reduced Water Exerts Superior Reactive Oxygen Species Scavenging Activity in HT1080 Cells Than the Equivalent Level of Hydrogen-dissolved Water.\u201d PLoS One<\/em>, vol. 12, no. 2, 2017.
https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28182635<\/a><\/p>

Hanaoka, Kokichi, et al. \u201cThe Mechanism of the Enhanced Antioxidant Effects Against Superoxide Anion Radicals of Reduced Water Produced by Electrolysis.\u201d Biophysical Chemistry<\/em>, vol. 107, no. 1, 2004, pp. 71-82.
https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/14871602<\/a><\/p>

Hanaoka, K. \u201cAntioxidant Effects of Reduced Water Produced by Electrolysis of Sodium Chloride Solutions.\u201d Journal of Applied Electrochemistry<\/em>, vol. 31, no. 12, 2001, pp. 1307-1313.
https:\/\/link.springer.com\/article\/10.1023\/A:1013825009701<\/a><\/p>

Huang, Kuo-Chin, et al. \u201cReduced Hemodialysis-Induced Oxidative Stress in End-Stage Renal Disease Patients by Electrolyzed Reduced Water.\u201d Kidney International<\/em>, vol. 64, no. 2, 2003, pp. 704\u2013714.
https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12846769<\/a><\/p>

KeramatiYazdi, Fatemeh, et al. \u201cRadioprotective Effect of Zamzam (Alkaline) Water: A Cytogenetic Study.\u201d Journal of Environmental Radioactivity<\/em>, vol. 167, 2017, pp. 166-169.
https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27839844<\/a><\/p>

Lee, Mi Young, et al. \u201cElectrolyzed-Reduced Water Protects Against Oxidative Damage to DNA, RNA, and Protein.\u201d Applied Biochemistry and Biotechnology<\/em>, vol. 135, no. 2, 2006, pp. 133-144.
https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17159237<\/a><\/p>

Shirahata, Sanetaka, et al. \u201cElectrolyzed\u2013Reduced Water Scavenges Active Oxygen Species and Protects DNA from Oxidative Damage.\u201d Biochemical and Biophysical Research Communications<\/em>, vol. 234, no. 1, 1997, pp. 269\u2013274.
https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9169001<\/a><\/p>

Yanagihara, Tomoyuki, et al. \u201cElectrolyzed Hydrogen-Saturated Water for Drinking Use Elicits an Antioxidative Effect: A Feeding Test with Rats.\u201d Bioscience, Biotechnology, and Biochemistry<\/em>, vol. 69, no. 10, 2005, pp. 1985-1987.
https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16244454<\/a><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tCancer<\/span><\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t
Chycki, Jakub, et al. \u201cAlkaline Water Improves Exercise-Induced Metabolic Acidosis and Enhances Anaerobic Exercise Performance in Combat Sport Athletes.\u201d PLoS One<\/em>, vol. 13, no. 11, 2018.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6242303\/<\/a>\n\nChycki, Jakub, et al. \u201cThe Effect of Mineral-Based Alkaline Water on Hydration Status and the Metabolic Response to Short-Term Anaerobic Exercise.\u201d Biology of Sport<\/em>, vol. 34, no. 3, 2017, pp. 255-261,\nhttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5676322\/<\/a>\n\nHeil, Daniel P. \u201cAcid-Base Balance and Hydration Status Following Consumption of Mineral-Based Alkaline Bottled Water.” Journal of the International Society of Sports Nutrition<\/em>, vol. 7, no. 9, 2010.\nhttps:\/\/jissn.biomedcentral.com\/articles\/10.1186\/1550-2783-7-29<\/a>\n\nIgnacio, Rosa, et al. \u201cClinical effect and mechanism of alkaline reduced water.\u201d Journal of Food and Drug Analysis<\/em>, vol. 20, 2012, pp. 394-397.\nhttps:\/\/www.researchgate.net\/publication\/286719002_Clinical_effect_and_mechanism_of_alkaline_reduced_water<\/a>\n\nRubik, Beverly. \u201cStudies and Observations on the Health Effects of Drinking Electrolyzed-Reduced Alkaline Water.\u201d Water and Society<\/em>, vol. 153, 2011.\nhttps:\/\/www.researchgate.net\/publication\/268238617_Studies_and_observations_on_the_health_effects\n_of_drinking_electrolyzed-reduced_alkaline_water<\/a>\n\nShirahata, Sanetaka, et al. \u201cAdvanced Research on the Health Benefit of Reduced Water.\u201d Trends in Food Science & Technology<\/em>, vol. 23, no. 2, 2012, pp. 124-131.\nhttps:\/\/www.sciencedirect.com\/science\/article\/pii\/S0924224411002408<\/a>\n\nWeidman, Joseph, et al. \u201cEffect of Electrolyzed High-PH Alkaline Water on Blood Viscosity in Healthy Adults.\u201d Journal of the International Society of Sports Nutrition<\/em>, vol. 13, no. 1, 2016.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5126823\/<\/a><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
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Ignacio, Rosa, et al. \u201cClinical effect and mechanism of alkaline reduced water.\u201d Journal of Food and Drug Analysis<\/em>, vol 20, 2012, pp. 394-397.\nhttps:\/\/www.researchgate.net\/publication\/286719002_Clinical_effect_and_mechanism_of_alkaline_reduced_water<\/a>\n\nRubik, B. \u201cStudies and Observations on the Health Effects of Drinking Electrolyzed-Reduced Alkaline Water.\u201d Water and Society<\/em>, 2011.\nhttps:\/\/www.researchgate.net\/publication\/268238617_Studies_and_observations_on_the_health_effects\n_of_drinking_electrolyzed-reduced_alkaline_water<\/a>\n\nWeidman, Joseph, et al. \u201cEffect of Electrolyzed High-PH Alkaline Water on Blood Viscosity in Healthy Adults.\u201d Journal of the International Society of Sports Nutrition<\/em>, vol. 13, no. 1, 2016.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5126823\/<\/a><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
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Nakyama M., et al. \u201cBiological Effects of Electrolyzed Water in Hemodialysis.\u201d Nephron Clinical Practice<\/em>, vol. 112, no.1, 2009, pp. 9-15.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19342864<\/a>\n\nYoon, Yang-Suk, et al. \u201cThe Melamine Excretion Effect of the Electrolyzed Reduced Water in Melamine-Fed Mice.\u201d Food and Chemical Toxicology<\/em>, vol. 49, no. 8, 2011, pp. 1814\u20131819.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21570445<\/a><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
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Tsai, Chia-Fang, et al. \u201cHepatoprotective Effect of Electrolyzed Reduced Water Against Carbon Tetrachloride-Induced Liver Damage in Mice.\u201d Food and Chemical Toxicology<\/em>, vol. 47, no. 8, 2009, pp. 2031-2036.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19477216<\/a><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tMetabolic syndrome<\/span><\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t
Ignacio, Rosa, et al. \u201cAnti-Obesity Effect of Alkaline Reduced Water in High Fat-Fed Obese Mice.\u201d Biological and Pharmaceutical Bulletin<\/em>, vol. 36, no. 7, 2013, pp. 1052\u20131059.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23811554<\/a>\n\nJackson, Karen, et al. \u201cEffects of Alkaline-Electrolyzed and Hydrogen-Rich Water, in a High-Fat-Diet Nonalcoholic Fatty Liver Disease Mouse Model.\u201d World Journal of Gastroenterology<\/em>, vol. 24, no. 45, 2018, pp. 5095\u20135108.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6288656\/<\/a>\n\nJin, Dan, et al. \u201cAnti-Diabetic Effect of Alkaline-Reduced Water on OLETF Rats.\u201d Bioscience, Biotechnology, and Biochemistry<\/em>, vol. 70, no. 1, 2006, pp. 31\u201337.\nhttps:\/\/www.tandfonline.com\/doi\/abs\/10.1271\/bbb.70.31<\/a>\n\nJin, Dan, et al. \u201cEffect of Mineral-induced Alkaline Reduced Water on Sprague-Dawley Rats Fed on High-fat Diet.\u201d Biomedical Science Letters<\/em>, vol. 12, no. 1, 2006, pp. 1-7.\nhttp:\/\/www.dbpia.co.kr\/journal\/articleDetail?nodeId=NODE00763600&language=ko_KR<\/a>\n\nKim, Mi-ja, and Hye Kyung Kim. \u201cAnti-Diabetic Effects of Electrolyzed Reduced Water in Streptozotocin-induced and Genetic Diabetic Mice.\u201d Life Sciences<\/em>, vol. 79, no. 24, 2006, pp. 2288-2292.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16945392<\/a>\n\nLi, Yupin, et al. \u201cSuppressive Effects of Electrolyzed Reduced Water on Alloxan-Induced Apoptosis and Type 1 Diabetes Mellitus.\u201d Cytotechnology<\/em>, vol. 63, no. 2, 2010, pp. 119\u2013131.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21063772<\/a>\n\nMinich, Deanna, and Bland Jeffrey. \u201cAcid-Alkaline Balance: Role in Chronic Disease and Detoxification.\u201d Alternative Therapies, <\/em>vol. 13, no. 4, 2007, pp. 2031-2036.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17658124<\/a>\n\nWatanabe, Toshi, et al. \u201cHistopathological Influence of Alkaline Ionized Water on Myocardial Muscle of Mother Rats.\u201d The Journal of Toxicological Sciences<\/em>, vol. 23, no. 15, 1998, pp. 411-417.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9922944<\/a>\n\nWatanabe, Toshi, et al. \u201cInfluence of Alkaline Ionized Water on Rat Erythrocyte Hexokinase Activity and Myocardium.\u201d The Journal of Toxicological Sciences<\/em>, vol. 22, no. 2, 1997, pp. 141\u2013152.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9198011<\/a><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tSepsis, gastritis and intestine<\/span><\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t
Anti, M., et al. \u201cEffects of Mineral-Water Supplementation on Gastric Emptying of Solids in Patients with Functional Dyspepsia Assessed with the 13C-Octanoic-Acid Breath Test.\u201d Hepato-gastroenterology<\/em>, vol. 51, no. 60, 2004, pp. 1856-1859.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15532843<\/a>\n\nBertoni Marcello, et al. \u201cEffects of a Bicarbonate-Alkaline Mineral Water on Gastric Functions and Functional Dyspepsia: A Preclinical and Clinical Study.\u201d Pharmacological Research<\/em>, vol. 46, no. 6, 2002, pp. 525-531.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12457626<\/a>\n\nFornai, Matteo, et al. \u201cEffects of a Bicarbonate-Alkaline Mineral Water on Digestive Motility in Experimental Models of Functional and Inflammatory Gastrointestinal Disorders.\u201d Methods and Findings in Experimental and Clinical Pharmacology<\/em>, vol.30, no. 4, 2008.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18773120<\/a>\n\nFujita, Ryo, et al. \u201cEffect of Molecular Hydrogen Saturated Alkaline Electrolyzed Water on Disuse Muscle Atrophy in Gastrocnemius Muscle.\u201d Journal of PHYSIOLOGICAL ANTHROPOLOGY<\/em>, vol. 30, no. 5, 2011, pp. 195\u2013201.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21963827<\/a>\n\nHigashimura, Yasuki, et al. \u201cEffects of Molecular Hydrogen-Dissolved Alkaline Electrolyzed Water on Intestinal Environmental in Mice.\u201d Med Gas Research<\/em>, vol. 8, no. 1, 2018, pp. 6-11.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5937304\/<\/a>\n\nKoufman, Jamie A. \u201cLow-Acid Diet for Recalcitrant Laryngopharyngeal Reflux: Therapeutic Benefits and Their Implications.\u201d Annals of Otology, Rhinology & Laryngology<\/em>, vol. 120, no. 5, 2011, pp. 281\u2013287.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21675582<\/a>\n\nKoufman, Jamie A., and Nikki Johnston. \u201cPotential Benefits of PH 8.8 Alkaline Drinking Water as an Adjunct in the Treatment of Reflux Disease.\u201d Annals of Otology, Rhinology & Laryngology<\/em>, vol. 121, no. 7, 2012, pp. 431\u2013434.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22844861<\/a>\n\nLee, Kyu Jae, et al. \u201cThe Immunological Effects of Electrolyzed Reduced Water on the Echinostoma Hortense Infection in C57BL\/6 Mice.\u201d Biological & Pharmaceutical Bulletin<\/em>, vol. 32, no. 3, 2009, pp. 456\u2013462.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19252295<\/a>\n\nNaito, Yuji, et al. \u201cChronic Administration with Electrolyzed Alkaline Water Inhibits Aspirin-induced Gastric Mucosal Injury in Rats through the Inhibition of Tumor Necrosis Factor-\u03b1 Expression.\u201d Journal of Clinical Biochemistry and Nutrition<\/em>, vol. 32, 2002, pp. 69-81.\nhttps:\/\/www.jstage.jst.go.jp\/article\/jcbn1986\/32\/0\/32_0_69\/_article<\/a>\n\nNassini, Romina, et al. \u201cA Bicarbonate-Alkaline Mineral Water Protects from Ethanol-Induced Hemorrhagic Gastric Lesions in Mice.\u201d Biological and Pharmaceutical Bulletin<\/em>, vol. 33, no. 8, 2010, pp. 1319-1323.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20686225<\/a>\n\nShin, Dong Woo, et al. \u201cEffects of Alkaline-Reduced Drinking Water on Irritable Bowel Syndrome with Diarrhea: A Randomized Double-Blind, Placebo-Controlled Pilot Study.\u201d Evidence-based complementary and alternative medicine:eCAM<\/em>, 2018.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5925025\/<\/a>\n\nVorobjeva, Nina. \u201cSelective Stimulation of the Growth of Anaerobic Microflora in the Human Intestinal Tract by Electrolyzed Reducing Water.\u201d Medical Hypotheses<\/em>, vol. 64, no. 3, 2005, pp. 543-546.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15617863<\/a>\n\nWatanabe, Toshi. \u201cEffect of Alkaline Ionized Water on Reproduction in Gestational and Lactational Rats.\u201d The Journal of Toxicological Sciences<\/em>, vol. 20, no. 2, 1995, pp. 135\u2013142.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/7473891<\/a>\n\nXue, Jinling, et al. \u201cDose-Dependent Inhibition of Gastric Injury by Hydrogen in Alkaline Electrolyzed Drinking Water.\u201d BMC Complementary and Alternative Medicine<\/em>, vol. 14, no. 1, 2014.\nhttps:\/\/bmccomplementalternmed.biomedcentral.com\/articles\/10.1186\/1472-6882-14-81<\/a><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
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SKIN AND RADIATION<\/strong>\n\nYoon, Kyung Su, et al. \u201cHistological Study on the Effect of Electrolyzed Reduced Water-Bathing on UVB Radiation-Induced Skin Injury in Hairless Mice.\u201d Biological & Pharmaceutical Bulletin<\/em>, vol. 34, no. 11, 2011, pp. 1671\u20131677.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22040878<\/a><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
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Burckhardt, Peter. \u201cThe Effect of the Alkali Load of Mineral Water on Bone Metabolism: Interventional Studies.\u201d The Journal of Nutrition<\/em>, vol. 138, no. 2, 2008, pp. 435-437.\nhttps:\/\/academic.oup.com\/jn\/article\/138\/2\/435S\/4665085<\/a>\n\nWatanabe,Toshi, et al. \u201cInfluences of Alkaline Ionized Water on Milk Yield, Body Weight ofOffspring, and Perinatal Dam in Rats.\u201d Journal of Toxicology Science<\/em>, vol. 23, no. 5, 1998, pp. 365-371.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9922938<\/a>\n\nWynn, Emma, et al. \u201cAlkaline Mineral Water Lowers Bone Resorption Even in Calcium Sufficiency: Alkaline Mineral Water and Bone Metabolism.\u201d Bone<\/em>, vol. 44, no. 1, 2009, pp. 120-124.\nhttps:\/\/doi.org\/10.1016\/j.bone.2008.09.007<\/a><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
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Kim, Mi-Ja, et al. \u201cPreservative Effect of Electrolyzed Reduced Water on Pancreatic Beta-cell Mass in Diabetic db\/db Mice.\u201d Biological and Pharmaceutical Bulletin<\/em>, vol. 30 no. 2, 2007, pp. 234-236.\nhttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17268057<\/a>\n\nOda, M., et al. \u201cElectrolyzed andNatural Reduced Water Exhibit Insulin-like Activity on Glucose Uptake intoMuscle Cells and Adipocytes.\u201d Animal Cell Technology: Products from Cells, Cells as Products<\/em>, 1999, pp. 425-427.\nhttps:\/\/link.springer.com\/chapter\/10.1007\/0-306-46875-1_90<\/a><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Hydrogen Water<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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1.Akhavan, O., et al.,\u00a0Hydrogen-rich water for green reduction of graphene oxide suspensions.<\/strong><\/a>\u00a0International Journal of Hydrogen Energy, 2015.\u00a040<\/strong>(16): p. 5553-5560.\n\n2.Berjak, P., et al.,\u00a0Cathodic amelioration of the adverse effects of oxidative stress accompanying procedures necessary for cryopreservation of embryonic axes of recalcitrant-seeded species.<\/strong><\/a>\u00a0Seed Science Research, 2011.\u00a021<\/strong>(3): p. 187-203.\n\n3.Hanaoka, K.,\u00a0Antioxidant effects of reduced water produced by electrolysis of sodium chloride solutions.<\/strong><\/a>Journal of Applied Electrochemistry, 2001.\u00a031<\/strong>(12): p. 1307-1313.\n\n4.Hanaoka, K., et al.,\u00a0The mechanism of the enhanced antioxidant effects against superoxide anion radicals of reduced water produced by electrolysis.<\/strong><\/a>\u00a0Biophysical Chemistry, 2004.\u00a0107<\/strong>(1): p. 71-82.\n\n5.Hiraoka, A., et al.,\u00a0In Vitro Physicochemical Properties of Neutral Aqueous Solution Systems (Water Products as Drinks) Containing Hydrogen Gas, 2-Carboxyethyl Germanium Sesquioxide, and Platinum Nanocolloid as Additives.<\/strong><\/a>\u00a0Journal of Health Science, 2010.\u00a056<\/strong>(2): p. 167-174.\n\n6.Hiraoka, A., et al.,\u00a0Studies on the properties and real existence of aqueous solution systems that are assumed to have antioxidant activities by the action of \u201cactive hydrogen\u201d<\/strong><\/a>\u2018. Journal of Health Science, 2004.\u00a050<\/strong>(5): p. 456-465.\n\n7.Kato, S., D. Matsuoka, and N. Miwa,\u00a0Antioxidant activities of nano-bubble hydrogen-dissolved water assessed by ESR and 2, 2\u2032-bipyridyl methods.<\/strong><\/a>\u00a0Materials Science and Engineering:, 2015.\u00a0C 53<\/strong>: p. 7-10.\n\n8.Lee, M.Y., et al.,\u00a0Electrolyzed-reduced water protects against oxidative damage to DNA, RNA, and protein.<\/strong><\/a>\u00a0Appl Biochem Biotechnol, 2006.\u00a0135<\/strong>(2): p. 133-44.\n\n9.Ohsawa, I., et al.,\u00a0Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.\u00a0<\/strong><\/a>Nat Med, 2007.\u00a013<\/strong>(6): p. 688-694.\n\n10.Ohta, S.,\u00a0Molecular hydrogen as a novel antioxidant: overview of the advantages of hydrogen for medical applications.<\/strong><\/a>\u00a0Methods Enzymol, 2015.\u00a0555<\/strong>: p. 289-317.\n\n11.Park, E.J., et al.,\u00a0Protective effect of electrolyzed reduced water on the paraquat-induced oxidative damage of human lymphocyte DNA.<\/strong><\/a>\u00a0Journal of the Korean Society for Applied\n\nBiological Chemistry, 2005.\u00a048<\/strong>(2): p. 155-160.\n\n12.Park, S.K., et al.,\u00a0Electrolyzed-reduced water confers increased resistance to environmental stresses.<\/strong><\/a>Molecular & Cellular Toxicology, 2012.\u00a08<\/strong>(3): p. 241-247.\n\n13.Park, S.K. and S.K. Park,\u00a0Electrolyzed-reduced water increases resistance to oxidative stress, fertility, and lifespan via insulin\/IGF-1-like signal in C. elegans.<\/strong><\/a>\u00a0Biol Res, 2013.\u00a046<\/strong>(2): p. 147-52.\n\n14.Penders, J., R. Kissner, and W.H. Koppenol,\u00a0ONOOH does not react with H2<\/strong><\/a>. Free Radic Biol Med, 2014.\n\n15.Qian, L., et al.,\u00a0Administration of hydrogen-rich saline protects mice from lethal acute graft-versus-host disease (aGVHD)<\/strong><\/a>. Transplantation, 2013.\u00a095<\/strong>(5): p. 658-62.\n\n16.Shi, Q.H., et al.,\u00a0Hydrogen Therapy Reduces Oxidative Stress-associated Risks Following Acute and Chronic Exposure to High-altitude Environment<\/strong><\/a>. Biomed Environ Sci, 2015.\u00a028<\/strong>(3): p. 239-41.\n\n17.Shirahata, S., et al.,\u00a0Electrolyzed-reduced water scavenges active oxygen species and protects DNA from oxidative damage.<\/strong><\/a>\u00a0Biochemical and Biophysical Research Communications, 1997.\u00a0234<\/strong>(1): p. 269-274.\n\n18.Yan, H., et al.,\u00a0Mechanism of the lifespan extension of Caenorhabditis elegans by electrolyzed reduced water\u2013participation of Pt nanoparticles.<\/strong><\/a>\u00a0Bioscience, Biotechnology, and Biochemistry, 2011.\u00a075<\/strong>(7): p. 1295-9.\n\n19.Yan, H., et al.,\u00a0electrolyzed reduced water prolongs caenorhabditis elegans lifespan, in Animal Cell Technology: Basic & Applied Aspects.<\/strong><\/a>\u00a02010, Springer Netherlands. p. 289-293.\n\n20.Yan, H.X., et al.,\u00a0Extension of the Lifespan of Caenorhabditis elegans by the Use of Electrolyzed Reduced Water.\u00a0<\/strong><\/a>Bioscience Biotechnology and Biochemistry, 2010.\u00a074<\/strong>(10): p. 2011-2015.\n\n21.Yanagihara, T., et al.,\u00a0Electrolyzed hydrogen-saturated water for drinking use elicits an antioxidative effect: a feeding test with rats.<\/strong><\/a>\u00a0Biosci Biotechnol Biochem, 2005.\u00a069<\/strong>(10): p. 1985-7.<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tBones<\/span><\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t
22.Cai, W.W., et al.,\u00a0Treatment with hydrogen molecule alleviates TNFalpha-induced cell injury in osteoblast<\/strong><\/a>. Mol Cell Biochem, 2013. 373(1-2): p. 1-9.\n\n23.Fujita, R., et al.,\u00a0Effect of molecular hydrogen saturated alkaline electrolyzed water on disuse muscle atrophy in gastrocnemius muscle.<\/strong><\/a>\u00a0Journal of Physiological Anthropology, 2011. 30(5): p. 195-201.\n\n24.Guo, J.D., et al.,\u00a0Hydrogen water consumption prevents osteopenia in ovariectomized rats.<\/strong><\/a>\u00a0Br J Pharmacol, 2013. 168(6): p. 1412-20.\n\n25.Hanaoka, T., et al.,\u00a0Molecular hydrogen protects chondrocytes from oxidative stress and indirectly alters gene expressions through reducing peroxynitrite derived from nitric oxide<\/strong><\/a>. Medical Gas Research, 2011. 1(1): p. 18.\n\n26.Itoh, T., et al.,\u00a0Molecular hydrogen inhibits lipopolysaccharide\/interferon gamma-induced nitric oxide production through modulation of signal transduction in macrophages<\/strong><\/a>. Biochemical and Biophysical Research Communications, 2011. 411(1): p. 143-9.\n\n27.Kawasaki, H., J.J. Guan, and K. Tamama,\u00a0Hydrogen gas treatment prolongs replicative lifespan of bone marrow multipotential stromal cells in vitro while preserving differentiation and paracrine potentials.<\/strong><\/a>Biochemical and Biophysical Research Communications, 2010. 397(3): p. 608-613.\n\n28.Kubota, M., et al.,\u00a0Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model.\u00a0<\/strong><\/a>Investigative Ophthalmology and Visual Science, 2011. 52(1): p. 427-33.\n\n29.Lekic, T., et al.,\u00a0Protective effect of hydrogen gas therapy after germinal matrix hemorrhage in neonatal rats.<\/strong><\/a>Acta Neurochir Suppl, 2011. 111: p. 237-41.\n\n30.Li, D.Z., et al.,\u00a0Treatment with hydrogen molecules prevents RANKL-induced osteoclast differentiation associated with inhibition of ROS formation and inactivation of MAPK, AKT and NF-kappa B pathways in murine RAW264.7 cells<\/strong><\/a>. J Bone Miner Metab, 2013.\n\n31.Sun, Y., et al.,\u00a0Treatment of hydrogen molecule abates oxidative stress and alleviates bone loss induced by modeled microgravity in rats.\u00a0<\/strong><\/a>Osteoporos Int, 2013. 24(3): p. 969-78.\n\n32.Takeuchi, S., et al.,\u00a0Hydrogen may inhibit collagen-induced platelet aggregation: an ex vivo and in vivo study.\u00a0<\/strong><\/a>Internal Medicine, 2012. 51(11): p. 1309-13.\n\n33.Xu, Z., et al.,\u00a0Anti-inflammation effects of hydrogen saline in LPS activated macrophages and carrageenan induced paw oedema<\/strong><\/a>. J Inflamm (Lond), 2012. 9: p. 2.\n\n34.Yuan, L., et al.,\u00a0Administration of hydrogen-rich saline in mice with allogeneic hematopoietic stem-cell transplantation<\/strong><\/a>. Med Sci Monit, 2015.\u00a021<\/strong>: p. 749-54.<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
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35.Bari, F., et al.,\u00a0Inhalation of Hydrogen Gas Protects Cerebrovascular Reactivity Against Moderate but Not Severe Perinatal Hypoxic Injury in Newborn Piglets.<\/strong><\/a>\u00a0Stroke, 2010.\u00a041<\/strong>(4): p. E323-E323.\n\n36.Cui, Y., et al.,\u00a0Hydrogen-rich saline attenuates neuronal ischemia-reperfusion injury by protecting mitochondrial function in rats.<\/strong><\/a>\u00a0J Surg Res, 2014.\n\n37.Dohi, K., et al.,\u00a0Molecular Hydrogen in Drinking Water Protects against Neurodegenerative Changes Induced by Traumatic Brain Injury.<\/strong><\/a>\u00a0PLoS One, 2014.\u00a09<\/strong>(9): p. e108034.\n\n38.Domoki, F., et al.,\u00a0Hydrogen is Neuroprotective and Preserves Cerebrovascular Reactivity in Asphyxiated Newborn Pigs.\u00a0<\/strong><\/a>Pediatric Research, 2010.\u00a068<\/strong>(5): p. 387-392.\n\n39.Eckermann, J.M., et al.,\u00a0Hydrogen is neuroprotective against surgically induced brain injury.\u00a0<\/strong><\/a>Medical Gas Research, 2011.\u00a01<\/strong>(1): p. 7.\n\n40.Feng, Y., et al.,\u00a0Hydrogen-rich saline prevents early neurovascular dysfunction resulting from inhibition of oxidative stress in STZ-diabetic rats.<\/strong><\/a>\u00a0Curr Eye Res, 2013.\u00a038<\/strong>(3): p. 396-404.\n\n41.Fu, Y., et al.,\u00a0Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson\u2019s disease.<\/strong><\/a>\u00a0Neuroscience Letters, 2009.\u00a0453<\/strong>: p. 81\u201385.\n\n42.Fujita, K., et al.,\u00a0Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson\u2019s disease.<\/strong><\/a>\u00a0PLoS One, 2009.\u00a04<\/strong>(9): p. e7247.\n\n43.Gu, Y., et al.,\u00a0Drinking Hydrogen Water Ameliorated Cognitive Impairment in Senescence-Accelerated Mice.<\/strong><\/a>Journal of Clinical Biochemistry and Nutrition, 2010.\u00a046<\/strong>(3): p. 269-276.\n\n44.Han, L., et al.,\u00a0Hydrogen-rich water protects against ischemic brain injury in rats by regulating calcium buffering proteins.<\/strong><\/a>\u00a0Brain Res, 2015.\n\n45.Hong, Y., et al.,\u00a0Beneficial effect of hydrogen-rich saline on cerebral vasospasm after experimental subarachnoid hemorrhage in rats.<\/strong><\/a>\u00a0J Neurosci Res, 2012.\u00a090<\/strong>(8): p. 1670-80.\n\n46.Hong, Y., et al.,\u00a0Neuroprotective effect of hydrogen-rich saline against neurologic damage and apoptosis in early brain injury following subarachnoid hemorrhage: possible role of the Akt\/GSK3beta signaling pathway.<\/strong><\/a>PLoS One, 2014.\u00a09<\/strong>(4): p. e96212.\n\n47.Hou, Z., et al.,\u00a0Hydrogen-rich saline protects against oxidative damage and cognitive deficits after mild traumatic brain injury.<\/strong><\/a>\u00a0Brain Res Bull, 2012.\u00a088<\/strong>(6): p. 560-5.\n\n48.Huang, G., et al.,\u00a0The neuroprotective effects of intraperitoneal injection of hydrogen in rabbits with cardiac arrest.<\/strong><\/a>\u00a0Resuscitation, 2013.\u00a084<\/strong>(5): p. 690-5.\n\n49.Hugyecz, M., et al.,\u00a0Hydrogen supplemented air inhalation reduces changes of prooxidant enzyme and gap junction protein levels after transient global cerebral ischemia in the rat hippocampus.<\/strong><\/a>\u00a0Brain Research, 2011.\u00a01404<\/strong>: p. 31-8.\n\n50.Ito, M., et al.,\u00a0Drinking hydrogen water and intermittent hydrogen gas exposure, but not lactulose or continuous hydrogen gas exposure, prevent 6-hydorxydopamine-induced Parkinson\u2019s disease in rats.<\/strong><\/a>\u00a0Med Gas Res, 2012.\u00a02<\/strong>(1): p. 15.\n\n51.Ji, X., et al.,\u00a0Beneficial effects of hydrogen gas in a rat model of traumatic brain injury via reducing oxidative stress.<\/strong><\/a>\u00a0Brain Research, 2010.\u00a01354<\/strong>: p. 196-205.\n\n52.Ji, X., et al.,\u00a0Protective effects of hydrogen-rich saline in a rat model of traumatic brain injury via reducing oxidative stress.\u00a0<\/strong><\/a>Journal of Surgical Research, 2012.\u00a0178<\/strong>(1): p. e9-16.\n\n53.Kashiwagi, T., et al.,\u00a0Suppression of Oxidative Stress-Induced Apoptosis of Neuronal Cells by Electrolyzed-Reduced Water.<\/strong><\/a>\u00a0Animal Cell Technology Meets Genomics, 2005.\u00a02<\/strong>: p. 257-260.\n\n54.Kashiwagi, T., et al.,\u00a0Electrochemically reduced water protects neural cells from oxidative damage.\u00a0<\/strong><\/a>Oxid Med Cell Longev, 2014.\u00a02014<\/strong>: p. 869121.\n\n55.Kobayashi, H., et al.,\u00a0Effects of Hydrogen Gas in a Mouse Cold Induced Brain Injury Model.<\/strong><\/a>\u00a0Journal of Neurotrauma, 2011.\u00a028<\/strong>(5): p. A64-A64.\n\n56.Kuroki, C., et al.,\u00a0Neuroprotective effects of hydrogen gas on brain in three types of stress models: alpha P-31-NMR study.<\/strong><\/a>\u00a0Neuroscience Research, 2009.\u00a065<\/strong>: p. S124-S124.\n\n57.Kuroki, C., et al.,\u00a0Neuroprotective effects of hydrogen gas on brain in three types of stress models: A P-31-NMR and ESR study.<\/strong><\/a>\u00a0Neuroscience Research, 2011.\u00a071<\/strong>: p. E406-E406.\n\n58.Li, J., et al.,\u00a0Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer\u2019s disease by reduction of oxidative stress.<\/strong><\/a>\u00a0Brain Res, 2010.\u00a01328<\/strong>: p. 152-161.\n\n59.Liu, F.T., et al.,\u00a0Molecular Hydrogen Suppresses Reactive Astrogliosis Related to Oxidative Injury during Spinal Cord Injury in Rats.<\/strong><\/a>\u00a0CNS Neurosci Ther, 2014.\n\n60.Liu, L., et al.,\u00a0Inhalation of hydrogen gas attenuates brain injury in mice with cecal ligation and puncture via inhibiting neuroinflammation, oxidative stress and neuronal apoptosis.<\/strong><\/a>\u00a0Brain Res, 2014.\u00a01589<\/strong>: p. 78-92.\n\n61.Liu, W., et al.,\u00a0Protective effects of hydrogen on fetal brain injury during maternal hypoxia.<\/strong><\/a>\u00a0Acta Neurochir Suppl, 2011.\u00a0111<\/strong>: p. 307-11.\n\n62.Manaenko, A., et al.,\u00a0Hydrogen inhalation is neuroprotective and improves functional outcomes in mice after intracerebral hemorrhage.\u00a0<\/strong><\/a>Acta Neurochir Suppl, 2011.\u00a0111<\/strong>: p. 179-83.\n\n63.Manaenko, A., et al.,\u00a0Hydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice.<\/strong><\/a>\u00a0Critical Care Medicine, 2013.\u00a041<\/strong>(5): p. 1266-75.\n\n64.Mano, Y., et al.,\u00a0Maternal molecular hydrogen administration ameliorates rat fetal hippocampal damage caused by in utero ischemia-reperfusion.<\/strong><\/a>\u00a0Free Radic Biol Med, 2014.\u00a069<\/strong>: p. 324-30.\n\n65.Matsumoto, A., et al.,\u00a0Oral \u2018hydrogen water\u2019 induces neuroprotective ghrelin secretion in mice.<\/strong><\/a>\u00a0Sci Rep, 2013.\u00a03<\/strong>: p. 3273.\n\n66.Mei, K., et al.,\u00a0Hydrogen protects rats from dermatitis caused by local radiation.<\/strong><\/a>\u00a0J Dermatolog Treat, 2014.\u00a025<\/strong>(2): p. 182-8.\n\n67.Nagata, K., et al.,\u00a0Consumption of Molecular Hydrogen Prevents the Stress-Induced Impairments in Hippocampus-Dependent Learning Tasks during Chronic Physical Restraint in Mice.\u00a0<\/strong><\/a>Neuropsychopharmacology, 2009.\u00a034<\/strong>(2): p. 501-508.\n\n68.Olah, O., et al.,\u00a0Delayed neurovascular dysfunction is alleviated by hydrogen in asphyxiated newborn pigs.<\/strong><\/a>Neonatology, 2013.\u00a0104<\/strong>(2): p. 79-86.\n\n69.Ono, H., et al.,\u00a0Improved brain MRI indices in the acute brain stem infarct sites treated with hydroxyl radical scavengers, Edaravone and hydrogen, as compared to Edaravone alone. A non-controlled study.<\/strong><\/a>\u00a0Medical Gas Research, 2011.\u00a01<\/strong>(1): p. 12.\n\n70.Ostojic, S.M.,\u00a0Targeting molecular hydrogen to mitochondria: Barriers and gateways.<\/strong><\/a>\u00a0Pharmacol Res, 2015.\u00a094<\/strong>: p. 51-3. (brain)\n\n71.Pshenichnyuk, S.A. and A.S. Komolov,\u00a0Dissociative Electron Attachment to Resveratrol as a Likely Pathway for Generation of the H2 Antioxidant Species Inside Mitochondria<\/strong><\/a>. The Journal of Physical Chemistry Letters, 2015.\u00a06<\/strong>(7): p. 1104-1110.\n\n72.Sato, Y., et al.,\u00a0Hydrogen-rich pure water prevents superoxide formation in brain slices of vitamin C-depleted SMP30\/GNL knockout mice.<\/strong><\/a>\u00a0Biochem Biophys Res Commun, 2008.\u00a0375<\/strong>(3): p. 346-350.\n\n73.Shen, L., et al.,\u00a0Hydrogen-rich saline is cerebroprotective in a rat model of deep hypothermic circulatory arrest.\u00a0<\/strong><\/a>Neurochemical Research, 2011.\u00a036<\/strong>(8): p. 1501-11.\n\n74.Shen, M.H., et al.,\u00a0Neuroprotective effect of hydrogen-rich saline in acute carbon monoxide poisoning.<\/strong><\/a>\u00a0CNS Neurosci Ther, 2013.\u00a019<\/strong>(5): p. 361-3.\n\n75.Spulber, S., et al.,\u00a0Molecular hydrogen reduces LPS-induced neuroinflammation and promotes recovery from sickness behaviour in mice.<\/strong><\/a>\u00a0PLoS One, 2012.\u00a07<\/strong>(7): p. e42078.\n\n76.Sun, Q., et al.,\u00a0Hydrogen-rich saline reduces delayed neurologic sequelae in experimental carbon monoxide toxicity.<\/strong><\/a>\u00a0Critical Care Medicine, 2011.\u00a039<\/strong>(4): p. 765-9.\n\n77.Takeuchi, S., et al.,\u00a0Hydrogen improves neurological function through attenuation of blood-brain barrier disruption in spontaneously hypertensive stroke-prone rats.<\/strong><\/a>\u00a0BMC Neurosci, 2015.\u00a016<\/strong>(1): p. 22. (brain)\n\n78.Ueda, Y., A. Nakajima, and T. Oikawa,\u00a0Hydrogen-Related Enhancement of In Vivo Antioxidant Ability in the Brain of Rats Fed Coral Calcium Hydride.<\/strong><\/a>\u00a0Neurochemical Research, 2010.\u00a035<\/strong>(10): p. 1510-1515.\n\n79.Wang, C., et al.,\u00a0Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-kappaB activation in a rat model of amyloid-beta-induced Alzheimer\u2019s disease.\u00a0<\/strong><\/a>Neuroscience Letters, 2011.\u00a0491<\/strong>(2): p. 127-32.\n\n80.Wang, T., et al.,\u00a0Oral intake of hydrogen-rich water ameliorated chlorpyrifos-induced neurotoxicity in rats.\u00a0<\/strong><\/a>Toxicol Appl Pharmacol, 2014.\n\n81.Wang, W., et al.,\u00a0Hydrogen rich saline reduces immune-mediated brain injury in rats with acute carbon monoxide poisoning.<\/strong><\/a>\u00a0Neurological Research, 2012.\u00a034<\/strong>(10): p. 1007-15.\n\n82.Xie, F. and X. Ma,\u00a0Molecular Hydrogen and its Potential Application in Therapy of Brain Disorders.<\/strong><\/a>\u00a0Brain Disord Ther, 2014: p. 2.\n\n83.Yan, H., et al.,\u00a0The neuroprotective effects of electrolyzed reduced water and its model water containing molecular hydrogen and Pt nanoparticles.<\/strong><\/a>\u00a0BMC Proc, 2011.\u00a05 Suppl 8<\/strong>: p. P69.\n\n84.Yamada, T., et al.,\u00a0Hydrogen supplementation of preservation solution improves viability of osteochondral grafts.<\/strong><\/a>\u00a0ScientificWorldJournal, 2014.\u00a02014<\/strong>: p. 109876. (bones)\n\n85.Yokoi, I., Neuroprotective effects of hydrogen gas on brain in three types of stress models: a P-31 NMR and ESR study. Neuroscience Research, 2010. 68: p. 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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tHuman<\/span><\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t
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338.Abe, T., et al.,\u00a0Hydrogen-rich University of Wisconsin solution attenuates renal cold ischemia-reperfusion injury.<\/strong><\/a>\u00a0Transplantation, 2012.\u00a094<\/strong>(1): p. 14-21.\n\n339.Cardinal, J.S., et al.,\u00a0Oral hydrogen water prevents chronic allograft nephropathy in rats.<\/strong><\/a>\u00a0Kidney International, 2010.\u00a077<\/strong>(2): p. 101-9.\n\n340.Homma, K., et al.,\u00a0Inhalation of Hydrogen Gas Is Beneficial for Preventing Contrast-Induced Acute Kidney Injury in Rats.<\/strong><\/a>\u00a0Nephron Exp Nephrol, 2015.\n\n341.Gu, H., et al.,\u00a0Pretreatment with hydrogen-rich saline reduces the damage caused by glycerol-induced rhabdomyolysis and acute kidney injury in rats.<\/strong><\/a>\u00a0J Surg Res, 2014.\u00a0188<\/strong>(1): p. 243-9.\n\n342.Katakura, M., et al., Hydrogen-rich water inhibits glucose and alpha,beta -dicarbonyl compound-induced reactive oxygen species production in the SHR.Cg-Leprcp\/NDmcr rat kidney. Medical Gas Research, 2012.\u00a02<\/strong>(1): p. 18.\n\n343.Kato, S., et al.,\u00a0Colloidal platinum in hydrogen-rich water exhibits radical-scavenging activity and improves blood fluidity.<\/strong><\/a>\u00a0J Nanosci Nanotechnol, 2012.\u00a012<\/strong>(5): p. 4019-27.\n\n344.Kitamura, A., et al.,\u00a0Experimental verification of protective effect of hydrogen-rich water against cisplatin-induced nephrotoxicity in rats using dynamic contrast-enhanced CT<\/strong><\/a>. British Journal of Radiology, 2010.\u00a083<\/strong>(990): p. 509-514.\n\n345.Liu, W., et al.,\u00a0A novel fluid resuscitation protocol: provide more protection on acute kidney injury during septic shock in rats.<\/strong><\/a>\u00a0Int J Clin Exp Med, 2014.\u00a07<\/strong>(4): p. 919-26.\n\n346.Matsushita, T., et al.,\u00a0Protective effect of hydrogen-rich water against gentamicin-induced nephrotoxicity in rats using blood oxygenation level-dependent MR imaging.<\/strong><\/a>\u00a0Magn Reson Med Sci, 2011.\u00a010<\/strong>(3): p. 169-76.\n\n347.Nakayama, M., et al.,\u00a0Less-oxidative hemodialysis solution rendered by cathode-side application of electrolyzed water.<\/strong><\/a>\u00a0Hemodial Int, 2007.\u00a011<\/strong>(3): p. 322-7.\n\n348.Ohaski, Y., et al.,\u00a0Electrolyzed water reduces urinary protein excretion in the streptozotocin induced diabetic Dahl salt sensitive rats.<\/strong><\/a>\u00a0The FASEB Journal, 2008.\u00a022<\/strong>: p. 947.17.\n\n349.Terawaki, H., et al.,\u00a0Effect of a hydrogen (H2)-enriched solution on the albumin redox of hemodialysis patients.<\/strong><\/a>\u00a0Hemodial Int, 2014.\u00a018<\/strong>(2): p. 459-66.\n\n350.Terawaki, H., et al.,\u00a0Successful treatment of encapsulating peritoneal sclerosis by hemodialysis and peritoneal lavage using dialysate containing dissolved hydrogen.<\/strong><\/a>\u00a0Perit Dial Int, 2015.\u00a035<\/strong>(1): p. 107-12.\n\n351.Xin, H.G., et al.,\u00a0Consumption of hydrogen-rich water alleviates renal injury in spontaneous hypertensive rats<\/strong><\/a>. Mol Cell Biochem, 2014.\u00a0392<\/strong>(1-2): p. 117-24.\n\n352.Zhu, W.J., et al.,\u00a0Amelioration of cardio-renal injury with aging in dahl salt-sensitive rats by H2-enriched electrolyzed water.\u00a0<\/strong><\/a>Med Gas Res, 2013.\u00a03<\/strong>(1): p. 26.<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tLiver<\/span><\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t
353.Gharib, B., et al.,\u00a0Anti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation.<\/strong><\/a>\u00a0C R Acad Sci III, 2001.\u00a0324<\/strong>(8): p. 719-724.\n\n354.Itoh, T., et al.,\u00a0Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells.<\/strong><\/a>\u00a0Biochem Biophys Res Commun, 2009.\u00a0389<\/strong>(4): p. 651-6.\n\n355.Kajiya, M., et al.,\u00a0Hydrogen from intestinal bacteria is protective for Concanavalin A-induced hepatitis.<\/strong><\/a>Biochem Biophys Res Commun, 2009.\u00a0386<\/strong>(2): p. 316-21.\n\n356.Koyama, Y., et al.,\u00a0Effects of Oral Intake of Hydrogen Water on Liver Fibrogenesis in Mice.<\/strong><\/a>\u00a0Hepatol Res, 2013.\n\n357.Koyama, Y., et al.,\u00a0Effects of oral intake of hydrogen water on liver fibrogenesis in mice.<\/strong><\/a>\u00a0Hepatol Res, 2014.\u00a044<\/strong>(6): p. 663-677.\n\n358.Lee, P.C., et al.,\u00a0Concomitant inhibition of oxidative stress and angiogenesis by chronic hydrogen-rich saline and N-acetylcysteine treatments improves systemic, splanchnic and hepatic hemodynamics of cirrhotic rats.<\/strong><\/a>Hepatol Res, 2014.\n\n359.Liu, G.D., et al.,\u00a0Molecular hydrogen regulates the expression of miR-9, miR-21 and miR-199 in LPS-activated retinal microglia cells.<\/strong><\/a>\u00a0Int J Ophthalmol, 2013.\u00a06<\/strong>(3): p. 280-5.\n\n360.Liu, Q., et al.,\u00a0Hydrogen-rich saline protects against liver injury in rats with obstructive jaundice.<\/strong><\/a>\u00a0Liver International, 2010.\u00a030<\/strong>(7): p. 958-968.\n\n361.Liu, Y., et al.,\u00a0Protective effects of hydrogen enriched saline on liver ischemia reperfusion injury by reducing oxidative stress and HMGB1 release.<\/strong><\/a>\u00a0BMC Gastroenterol, 2014.\u00a014<\/strong>: p. 12.\n\n362.Matsuno, N., et al.,\u00a0Beneficial effects of hydrogen gas on porcine liver reperfusion injury with use of total vascular exclusion and active venous bypass.<\/strong><\/a>\u00a0Transplant Proc, 2014.\u00a046<\/strong>(4): p. 1104-6.\n\n363.Nishimura, N., et al.,\u00a0Pectin and high-amylose maize starch increase caecal hydrogen production and relieve hepatic ischaemia-reperfusion injury in rats.<\/strong><\/a>\u00a0Br J Nutr, 2012.\u00a0107<\/strong>(4): p. 485-92.\n\n364.Park, S.K., et al.,\u00a0Electrolyzed-reduced water inhibits acute ethanol-induced hangovers in Sprague-Dawley rats.<\/strong><\/a>\u00a0Biomed Res, 2009.\u00a030<\/strong>(5): p. 263-9.\n\n365.Shen, M.H., et al.,\u00a0Hydrogen as a novel and effective treatment of acute carbon monoxide poisoning.<\/strong><\/a>\u00a0Medical Hypotheses, 2010.\u00a075<\/strong>(2): p. 235-237.\n\n366.Sun, H., et al.,\u00a0The protective role of hydrogen-rich saline in experimental liver injury in mice.\u00a0<\/strong><\/a>Journal of Hepatology, 2011.\u00a054<\/strong>(3): p. 471-80.\n\n367.Tan, Y.C., et al.,\u00a0Hydrogen-rich saline attenuates postoperative liver failure after major hepatectomy in rats.<\/strong><\/a>Clin Res Hepatol Gastroenterol, 2014.\u00a038<\/strong>(3): p. 337-45.\n\n368.Tange, Y., S. Takesawa, and S. Yoshitake,\u00a0Dialysate with high dissolved hydrogen facilitates dissociation of indoxyl sulfate from albumin.<\/strong><\/a>\u00a0Nephrourol Mon, 2015.\u00a07<\/strong>(2): p. e26847.\n\n369.Tsai, C.F., et al.,\u00a0Hepatoprotective effect of electrolyzed reduced water against carbon tetrachloride-induced liver damage in mice.<\/strong><\/a>\u00a0Food Chem Toxicol, 2009.\u00a047<\/strong>(8): p. 2031-6.\n\n370.Wang, W., et al.,\u00a0Effects of hydrogen-rich saline on rats with acute carbon monoxide poisoning.<\/strong><\/a>\u00a0Journal of Emergency Medicine, 2013.\u00a044<\/strong>(1): p. 107-15.\n\n371.Xiang, L., et al.,\u00a0Inhalation of hydrogen gas reduces liver injury during major hepatotectomy in swine.<\/strong><\/a>\u00a0World Journal of Gastroenterology, 2012.\u00a018<\/strong>(37): p. 5197-5204.\n\n372.Xu, X.F. and J. Zhang,\u00a0Saturated hydrogen saline attenuates endotoxin-induced acute liver dysfunction in rats<\/strong><\/a>. Physiol Res, 2013.\u00a062<\/strong>(4): p. 395-403.\n\n373.Zhang, C.B., et al.,\u00a0Hydrogen gas inhalation protects against liver ischemia\/reperfusion injury by activating the NF-\u03baB signaling pathway<\/strong><\/a>. Experimental and Therapeutic Medicine, 2015.\u00a09<\/strong>(6): p. 2114-2120.\n\n374.Zhang, J.Y., et al.,\u00a0Hydrogen-rich water protects against acetaminophen-induced hepatotoxicity in mice.<\/strong><\/a>World J Gastroenterol, 2015.\u00a021<\/strong>(14): p. 4195-209.<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
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375.Du, Z., et al.,\u00a0Protective effects of hydrogen-rich saline in uncontrolled hemorrhagic shock.<\/strong><\/a>\u00a0Journal of Surgical Research, 2014.\u00a0In press<\/strong>.\n\n376.Fang, Y., et al.,\u00a0Hydrogen-rich saline protects against acute lung injury induced by extensive burn in rat model.\u00a0<\/strong><\/a>Journal of Burn Care and Research, 2011.\u00a032<\/strong>(3): p. e82-91.\n\n377.Haam, S., et al.,\u00a0The effects of hydrogen gas inhalation during ex vivo lung perfusion on donor lungs obtained after cardiac deathdagger.<\/strong><\/a>\u00a0Eur J Cardiothorac Surg, 2015.\n\n378.Huang, C.S., et al.,\u00a0Hydrogen inhalation ameliorates ventilator-induced lung injury.<\/strong><\/a>\u00a0Critical Care, 2010.\u00a014<\/strong>(6): p. 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Nan Fang Yi Ke Da Xue Xue Bao, 2012.\u00a032<\/strong>(8): p. 1211-3.\n\n383.Liu, S., et al.,\u00a0Consumption of hydrogen water reduces paraquat-induced acute lung injury in rats.<\/strong><\/a>\u00a0Journal of Biomedicine & Biotechnology, 2011.\u00a02011<\/strong>: p. 305086.\n\n384.Liu, R., et al.,\u00a0Lung inflation with hydrogen during the cold ischemia phase decreases lung graft injury in rats.<\/strong><\/a>Exp Biol Med (Maywood), 2015.\n\n385.Liu, S.L., et al.,\u00a0Hydrogen Therapy may be a Novel and Effective Treatment for COPD.<\/strong><\/a>\u00a0Front Pharmacol, 2011.\u00a02<\/strong>: p. 19.\n\n386.Liu, H., et al.,\u00a0Combination therapy with nitric oxide and molecular hydrogen in a murine model of acute lung injury.<\/strong><\/a>\u00a0Shock, 2015.\u00a043<\/strong>(5): p. 504-11.\n\n387.Liu, W., et al.,\u00a0Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury.\u00a0<\/strong><\/a>World J Gastroenterol, 2013.\u00a019<\/strong>(4): p. 492-502.\n\n388.Ning, Y., et al.,\u00a0Attenuation of cigarette smoke-induced airway mucus production by hydrogen-rich saline in rats.<\/strong><\/a>\u00a0PLoS One, 2013.\u00a08<\/strong>(12): p. e83429.\n\n389.Noda, K., et al.,\u00a0Hydrogen Preconditioning During Ex Vivo Lung Perfusion Improves the Quality of Lung Grafts in Rats.<\/strong><\/a>\u00a0Transplantation 2014.\u00a0??<\/strong>\n\n390.Qiu, X., et al.,\u00a0Hydrogen inhalation ameliorates lipopolysaccharide-induced acute lung injury in mice.<\/strong><\/a>\u00a0Int Immunopharmacol, 2011.\u00a011<\/strong>(12): p. 2130-7.\n\n391.Qiu, X.C., et al.,\u00a0[Effect of hydrogen-rich saline on blood pressure and antioxidant ability of lung tissue in scalded rats following delayed resuscitation]<\/strong><\/a>. 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402.Abe, M., et al.,\u00a0Suppressive Effect of ERW on Lipid Peroxidation and Plasma Triglyceride Level, in Animal Cell Technology: Basic & Applied Aspects.<\/strong><\/a>\u00a0S. Netherlands, Editor. 2010. p. 315-321.\n\n403.Amitani, H., et al.,\u00a0Hydrogen Improves Glycemic Control in Type1 Diabetic Animal Model by Promoting Glucose Uptake into Skeletal Muscle.<\/strong><\/a>\u00a0PLoS One, 2013.\u00a08<\/strong>(1).\n\n404.Baek, D.-H.,\u00a0Antibacterial Activity of Hydrogen-rich Water Against Oral Bacteria.<\/strong><\/a>\u00a02013.\n\n405.Chao, Y.C. and M.T. 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British Journal of Anaesthesia, 2012.\u00a0108<\/strong>(3): p. 538-539.\n\n514.Xie, K., et al.,\u00a0Hydrogen gas presents a promising therapeutic strategy for sepsis.<\/strong><\/a>\u00a0Biomed Res Int, 2014.\u00a02014<\/strong>: p. 807635.\n\n515.Xue, J., et al.,\u00a0Dose-dependent inhibition of gastric injury by hydrogen in alkaline electrolyzed drinking water.\u00a0<\/strong><\/a>BMC Complementary and Alternative Medicine, 2014.\u00a014<\/strong>(1): p. 81.\n\n516.Zhang, J.Y., et al.,\u00a0Protective role of hydrogen-rich water on aspirin-induced gastric mucosal damage in rats.\u00a0<\/strong><\/a>World J Gastroenterol, 2014.\u00a020<\/strong>(6): p. 1614-22.<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tSkin & Radiation<\/span><\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t
517.Chuai, Y., et al.,\u00a0Hydrogen-rich saline attenuates radiation-induced male germ cell loss in mice through reducing hydroxyl radicals.<\/strong><\/a>\u00a0Biochemical Journal, 2012.\u00a0442<\/strong>(1): p. 49-56.\n\n518.Chuai, Y., et al.,\u00a0Hydrogen-rich saline protects spermatogenesis and hematopoiesis in irradiated BALB\/c mice.<\/strong><\/a>\u00a0Med Sci Monit, 2012.\u00a018<\/strong>(3): p. BR89-94.\n\n519.Guo, S.X., et al.,\u00a0Beneficial effects of hydrogen-rich saline on early burn-wound progression in rats.<\/strong><\/a>\u00a0PLoS One, 2015.\u00a010<\/strong>(4): p. e0124897.\n\n520.Ignacio, R.M., et al.,\u00a0The Drinking Effect of Hydrogen Water on Atopic Dermatitis Induced by Dermatophagoides farinae Allergen in NC\/Nga Mice.<\/strong><\/a>\u00a0Evid Based Complement Alternat Med, 2013.\u00a02013<\/strong>: p. 538673.\n\n521.Ignacio, R.M., et al.,\u00a0The balneotherapy effect of hydrogen reduced water on UVB-mediated skin injury in hairless mice.<\/strong><\/a>\u00a0Molecular & Cellular Toxicology, 2013.\u00a09<\/strong>(1): p. 15-21.\n\n522.Jiang, Z., et al.,\u00a0Protection by hydrogen against gamma ray-induced testicular damage in rats.<\/strong><\/a>\u00a0Basic Clin Pharmacol Toxicol, 2013.\u00a0112<\/strong>(3): p. 186-91.\n\n523.Kato, S., et al.,\u00a0Hydrogen-rich electrolyzed warm water represses wrinkle formation against UVA ray together with type-I collagen production and oxidative-stress diminishment in fibroblasts and cell-injury prevention in keratinocytes.<\/strong><\/a>\u00a0J Photochem Photobiol B, 2012.\u00a0106<\/strong>: p. 24-33.\n\n524.Kitamura, T., H. Todo, and K. Sugibayashi,\u00a0Effect of several electrolyzed waters on the skin permeation of lidocaine, benzoic Acid, and isosorbide mononitrate.<\/strong><\/a>\u00a0Drug Development and Industrial Pharmacy, 2009.\u00a035<\/strong>(2): p. 145-53.\n\n525.Liu, Y.Q., et al.,\u00a0Hydrogen-rich saline attenuates skin ischemia\/reperfusion induced apoptosis via regulating Bax\/Bcl-2 ratio and ASK-1\/JNK pathway<\/strong><\/a>. Reconstructive & Aesthetic Surgery, 2015.\n\n526.Ostojic, S.M.,\u00a0Eumelanin-driven production of molecular hydrogen: A novel element of skin defense?<\/strong><\/a>\u00a0Med Hypotheses, 2015. (skin)\n\n527.Qian, L.R., et al.,\u00a0Radioprotective effect of hydrogen in cultured cells and mice.<\/strong><\/a>\u00a0Free Radic Res, 2010.\u00a044<\/strong>(3): p. 275-282.\n\n528.Qian, L.R., et al.,\u00a0Hydrogen-rich PBS protects cultured human cells from ionizing radiation-induced cellular damage<\/strong><\/a>. Nuclear Technology & Radiation Protection, 2010.\u00a025<\/strong>(1): p. 23-29.\n\n529.Wang, X., et al.,\u00a0Hydrogen-rich saline resuscitation alleviates inflammation induced by severe burn with delayed resuscitation.<\/strong><\/a>\u00a0Burns, 2015.\u00a041<\/strong>(2): p. 379-85.\n\n530.Wei, L., et al.,\u00a0Hydrogen-rich saline protects retina against glutamate-induced excitotoxic injury in guinea pig.<\/strong><\/a>Experimental Eye Research, 2012.\u00a094<\/strong>(1): p. 117-27.\n\n531.Yang, Y., et al.,\u00a0Hydrogen-rich saline protects immunocytes from radiation-induced apoptosis.<\/strong><\/a>\u00a0Med Sci Monit, 2012.\u00a018<\/strong>(4): p. BR144-8.\n\n532.Yang, Y., et al.,\u00a0Molecular hydrogen protects human lymphocyte AHH-1 cells against C heavy ion radiation.\u00a0<\/strong><\/a>International Journal of Radiation Biology, 2013.\n\n533.Yoon, K.S., et al.,\u00a0Histological study on the effect of electrolyzed reduced water-bathing on UVB radiation-induced skin injury in hairless mice.<\/strong><\/a>\u00a0Biological and Pharmaceutical Bulletin, 2011.\u00a034<\/strong>(11): p. 1671-7.\n\n534.Yoon, Y.S., et al.,\u00a0Positive Effects of hydrogen water on 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC\/Nga mice.<\/strong><\/a>\u00a0Biol Pharm Bull, 2014.\u00a037<\/strong>(9): p. 1480-5.\n\n535.Yu, W.T., et al.,\u00a0Hydrogen-enriched water restoration of impaired calcium propagation by arsenic in primary keratinocytes<\/strong><\/a>. Journal of Asian Earth Sciences, 2013.\u00a077<\/strong>: p. 342-348.\n\n536.Zhao, L., et al.,\u00a0Hydrogen protects mice from radiation induced thymic lymphoma in BALB\/c mice.<\/strong><\/a>International Journal of Biological Sciences, 2011.\u00a07<\/strong>(3): p. 297-300.\n\n537.Zhao, S., et al.,\u00a0Protective effect of hydrogen-rich saline against radiation-induced immune dysfunction.\u00a0<\/strong><\/a>J Cell Mol Med, 2014.\u00a018<\/strong>(5): p. 938-46.<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
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538.Chen, C.W., et al.,\u00a0Hydrogen-Rich Saline Protects Against Spinal Cord Injury in Rats.<\/strong><\/a>\u00a0Neurochemical Research, 2010.\u00a035<\/strong>(7): p. 1111-1118.\n\n539.Chen, H., et al.,\u00a0Hydrogen-rich saline ameliorates the severity of L-arginine-induced acute pancreatitis in rats.\u00a0<\/strong><\/a>Biochem Biophys Res Commun, 2010.\u00a0393<\/strong>(2): p. 308-313.\n\n540.Hong, Y., S. Chen, and J.M. Zhang,\u00a0[Research advances on hydrogen therapy in nervous system diseases].\u00a0<\/strong><\/a>Zhejiang Da Xue Xue Bao Yi Xue Ban, 2010.\u00a039<\/strong>(6): p. 638-43.\n\n541.Ren, J., et al.,\u00a0Hydrogen-rich saline reduces the oxidative stress and relieves the severity of trauma-induced acute pancreatitis in rats.\u00a0<\/strong><\/a>J Trauma Acute Care Surg, 2012.\u00a072<\/strong>(6): p. 1555-61.\n\n542.Ren, J.D., et al.,\u00a0Hydrogen-rich saline inhibits NLRP3 inflammasome activation and attenuates experimental acute pancreatitis in mice.<\/strong><\/a>\u00a0Mediators Inflamm, 2014.\u00a02014<\/strong>: p. 930894.\n\n543.Zhang, D.Q. and J.H. Zhu,\u00a0[Experimental studies of effects of hydrogen-rich saline in rats with severe acute pancreatitis]<\/strong><\/a>. Zhonghua Yi Xue Za Zhi, 2012.\u00a092<\/strong>(34): p. 2436-40.\n\n544.Zhang, D.Q., H. Feng, and W.C. Chen,\u00a0Effects of hydrogen-rich saline on taurocholate-induced acute pancreatitis in rat.<\/strong><\/a>\u00a0Evid Based Complement Alternat Med, 2013.\u00a02013<\/strong>: p. 731932.<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Studies Alkaline Water Antioxidant Hamasaki, Takeki, et al. \u201cElectrochemically Reduced Water Exerts Superior Reactive Oxygen Species Scavenging Activity in HT1080 Cells Than the Equivalent Level of Hydrogen-dissolved Water.\u201d PLoS One, vol. 12, no. 2, 2017.https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28182635 Hanaoka, Kokichi, et al. \u201cThe Mechanism of the Enhanced Antioxidant Effects Against Superoxide Anion Radicals of Reduced Water Produced by Electrolysis.\u201d Biophysical Chemistry, vol. 107, no. 1, 2004, pp. 71-82.https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/14871602 Hanaoka, K. \u201cAntioxidant Effects of Reduced Water Produced by Electrolysis of Sodium Chloride Solutions.\u201d Journal of Applied Electrochemistry, vol. 31, no. 12, 2001, pp. 1307-1313.https:\/\/link.springer.com\/article\/10.1023\/A:1013825009701 Huang, Kuo-Chin, et al. \u201cReduced Hemodialysis-Induced Oxidative Stress in End-Stage Renal Disease Patients by Electrolyzed Reduced Water.\u201d Kidney International, vol. 64, no. 2, 2003, pp. 704\u2013714.https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12846769 KeramatiYazdi, Fatemeh, et al. \u201cRadioprotective Effect of Zamzam (Alkaline) Water: A Cytogenetic Study.\u201d Journal of Environmental Radioactivity, vol. 167, 2017, pp. 166-169.https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27839844 Lee, Mi Young, et al. \u201cElectrolyzed-Reduced Water Protects Against Oxidative Damage to DNA, RNA, and Protein.\u201d Applied Biochemistry and Biotechnology, vol. 135, no. 2, 2006, pp. 133-144.https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17159237 Shirahata, Sanetaka, et al. \u201cElectrolyzed\u2013Reduced Water Scavenges Active Oxygen Species and Protects DNA from Oxidative Damage.\u201d Biochemical and Biophysical Research Communications, vol. 234, no. 1, 1997, pp. 269\u2013274.https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9169001 Yanagihara, Tomoyuki, et al. \u201cElectrolyzed Hydrogen-Saturated Water for Drinking Use Elicits an Antioxidative Effect: A Feeding Test with Rats.\u201d Bioscience, Biotechnology, and Biochemistry, vol. 69, no. 10, 2005, pp. 1985-1987.https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16244454 Cancer Chycki, Jakub, et al. \u201cAlkaline Water Improves Exercise-Induced Metabolic Acidosis and Enhances Anaerobic Exercise Performance in Combat Sport Athletes.\u201d PLoS One, vol. 13, no. 11, 2018. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6242303\/ Chycki, Jakub, et al. \u201cThe Effect of Mineral-Based Alkaline Water on Hydration Status and the Metabolic Response to Short-Term Anaerobic Exercise.\u201d Biology of Sport, vol. 34, no. 3, 2017, pp. 255-261, https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5676322\/ Heil, Daniel P. \u201cAcid-Base Balance and Hydration Status Following Consumption of Mineral-Based Alkaline Bottled Water.” Journal of the International Society of Sports Nutrition, vol. 7, no. 9, 2010. https:\/\/jissn.biomedcentral.com\/articles\/10.1186\/1550-2783-7-29 Ignacio, Rosa, et al. \u201cClinical effect and mechanism of alkaline reduced water.\u201d Journal of Food and Drug Analysis, vol. 20, 2012, pp. 394-397. https:\/\/www.researchgate.net\/publication\/286719002_Clinical_effect_and_mechanism_of_alkaline_reduced_water Rubik, Beverly. \u201cStudies and Observations on the Health Effects of Drinking Electrolyzed-Reduced Alkaline Water.\u201d Water and Society, vol. 153, 2011. https:\/\/www.researchgate.net\/publication\/268238617_Studies_and_observations_on_the_health_effects _of_drinking_electrolyzed-reduced_alkaline_water Shirahata, Sanetaka, et al. \u201cAdvanced Research on the Health Benefit of Reduced Water.\u201d Trends in Food Science & Technology, vol. 23, no. 2, 2012, pp. 124-131. https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0924224411002408 Weidman, Joseph, et al. \u201cEffect of Electrolyzed High-PH Alkaline Water on Blood Viscosity in Healthy Adults.\u201d Journal of the International Society of Sports Nutrition, vol. 13, no. 1, 2016. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5126823\/ Human Ignacio, Rosa, et al. \u201cClinical effect and mechanism of alkaline reduced water.\u201d Journal of Food and Drug Analysis, vol 20, 2012, pp. 394-397. https:\/\/www.researchgate.net\/publication\/286719002_Clinical_effect_and_mechanism_of_alkaline_reduced_water Rubik, B. \u201cStudies and Observations on the Health Effects of Drinking Electrolyzed-Reduced Alkaline Water.\u201d Water and Society, 2011. https:\/\/www.researchgate.net\/publication\/268238617_Studies_and_observations_on_the_health_effects _of_drinking_electrolyzed-reduced_alkaline_water Weidman, Joseph, et al. \u201cEffect of Electrolyzed High-PH Alkaline Water on Blood Viscosity in Healthy Adults.\u201d Journal of the International Society of Sports Nutrition, vol. 13, no. 1, 2016. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5126823\/ Kidney Nakyama M., et al. \u201cBiological Effects of Electrolyzed Water in Hemodialysis.\u201d Nephron Clinical Practice, vol. 112, no.1, 2009, pp. 9-15. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19342864 Yoon, Yang-Suk, et al. \u201cThe Melamine Excretion Effect of the Electrolyzed Reduced Water in Melamine-Fed Mice.\u201d Food and Chemical Toxicology, vol. 49, no. 8, 2011, pp. 1814\u20131819. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21570445 Liver Tsai, Chia-Fang, et al. \u201cHepatoprotective Effect of Electrolyzed Reduced Water Against Carbon Tetrachloride-Induced Liver Damage in Mice.\u201d Food and Chemical Toxicology, vol. 47, no. 8, 2009, pp. 2031-2036. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19477216 Metabolic syndrome Ignacio, Rosa, et al. \u201cAnti-Obesity Effect of Alkaline Reduced Water in High Fat-Fed Obese Mice.\u201d Biological and Pharmaceutical Bulletin, vol. 36, no. 7, 2013, pp. 1052\u20131059. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23811554 Jackson, Karen, et al. \u201cEffects of Alkaline-Electrolyzed and Hydrogen-Rich Water, in a High-Fat-Diet Nonalcoholic Fatty Liver Disease Mouse Model.\u201d World Journal of Gastroenterology, vol. 24, no. 45, 2018, pp. 5095\u20135108. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6288656\/ Jin, Dan, et al. \u201cAnti-Diabetic Effect of Alkaline-Reduced Water on OLETF Rats.\u201d Bioscience, Biotechnology, and Biochemistry, vol. 70, no. 1, 2006, pp. 31\u201337. https:\/\/www.tandfonline.com\/doi\/abs\/10.1271\/bbb.70.31 Jin, Dan, et al. \u201cEffect of Mineral-induced Alkaline Reduced Water on Sprague-Dawley Rats Fed on High-fat Diet.\u201d Biomedical Science Letters, vol. 12, no. 1, 2006, pp. 1-7. http:\/\/www.dbpia.co.kr\/journal\/articleDetail?nodeId=NODE00763600&language=ko_KR Kim, Mi-ja, and Hye Kyung Kim. \u201cAnti-Diabetic Effects of Electrolyzed Reduced Water in Streptozotocin-induced and Genetic Diabetic Mice.\u201d Life Sciences, vol. 79, no. 24, 2006, pp. 2288-2292. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16945392 Li, Yupin, et al. \u201cSuppressive Effects of Electrolyzed Reduced Water on Alloxan-Induced Apoptosis and Type 1 Diabetes Mellitus.\u201d Cytotechnology, vol. 63, no. 2, 2010, pp. 119\u2013131. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21063772 Minich, Deanna, and Bland Jeffrey. \u201cAcid-Alkaline Balance: Role in Chronic Disease and Detoxification.\u201d Alternative Therapies, vol. 13, no. 4, 2007, pp. 2031-2036. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17658124 Watanabe, Toshi, et al. \u201cHistopathological Influence of Alkaline Ionized Water on Myocardial Muscle of Mother Rats.\u201d The Journal of Toxicological Sciences, vol. 23, no. 15, 1998, pp. 411-417. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9922944 Watanabe, Toshi, et al. \u201cInfluence of Alkaline Ionized Water on Rat Erythrocyte Hexokinase Activity and Myocardium.\u201d The Journal of Toxicological Sciences, vol. 22, no. 2, 1997, pp. 141\u2013152. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9198011 Sepsis, gastritis and intestine Anti, M., et al. \u201cEffects of Mineral-Water Supplementation on Gastric Emptying of Solids in Patients with Functional Dyspepsia Assessed with the 13C-Octanoic-Acid Breath Test.\u201d Hepato-gastroenterology, vol. 51, no. 60, 2004, pp. 1856-1859. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15532843 Bertoni Marcello, et al. \u201cEffects of a Bicarbonate-Alkaline Mineral Water on Gastric Functions and Functional Dyspepsia: A Preclinical and Clinical Study.\u201d Pharmacological Research, vol. 46, no. 6, 2002, pp. 525-531. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12457626 Fornai, Matteo, et al. \u201cEffects of a Bicarbonate-Alkaline Mineral Water on Digestive Motility in Experimental Models of Functional and Inflammatory Gastrointestinal Disorders.\u201d Methods and Findings in Experimental and Clinical Pharmacology, vol.30, no. 4, 2008. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18773120 Fujita, Ryo, et al. \u201cEffect of Molecular Hydrogen Saturated Alkaline Electrolyzed Water on Disuse Muscle Atrophy in Gastrocnemius Muscle.\u201d Journal of PHYSIOLOGICAL ANTHROPOLOGY, vol. 30, no. 5, 2011, pp. 195\u2013201. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21963827 Higashimura, Yasuki, et al. \u201cEffects of Molecular Hydrogen-Dissolved Alkaline Electrolyzed Water on Intestinal Environmental in Mice.\u201d Med Gas Research, vol. 8, no. 1, 2018, pp. 6-11. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5937304\/ Koufman, Jamie A. \u201cLow-Acid Diet for Recalcitrant Laryngopharyngeal Reflux: Therapeutic Benefits and Their Implications.\u201d Annals of Otology, Rhinology & Laryngology,Read More »studies<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"neve_meta_sidebar":"full-width","neve_meta_container":"full-width","neve_meta_enable_content_width":"on","neve_meta_content_width":70,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"on","footnotes":""},"class_list":["post-190","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/ionfarms.com\/wp-json\/wp\/v2\/pages\/190"}],"collection":[{"href":"https:\/\/ionfarms.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ionfarms.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ionfarms.com\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/ionfarms.com\/wp-json\/wp\/v2\/comments?post=190"}],"version-history":[{"count":0,"href":"https:\/\/ionfarms.com\/wp-json\/wp\/v2\/pages\/190\/revisions"}],"wp:attachment":[{"href":"https:\/\/ionfarms.com\/wp-json\/wp\/v2\/media?parent=190"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}